Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.57 |
| ▸ | NCF1 | P14598 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | CCR8 | P51685 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071707 | 0.92 | NR4A2 (0.59) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL30913269 | 0.81 | NR4A2 (0.55) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL563282 | 0.80 | NR4A2 (0.41) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL23546584 | 0.80 | NR4A2 (0.44) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL3350823 | 0.80 | NCF1 (0.60) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL10949867 | 0.78 | NR4A2 (0.44) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL30668493 | 0.78 | NR4A2 (0.68) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL6629560 | 0.78 | NR4A2 (0.68) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL16381310 | 0.77 | NR4A2 (0.48) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 | |
| SCHEMBL3350818 | 0.77 | CCR1 (0.62) | NR4A2NCF1HSP90AA1HSP90AB1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207801-B1 | METHODS OF INHIBITING VIRAL INFECTION | FUNCTIONAL GENETICS INC (US) | 2013-04-17 | — | — | EP | disclosed |
| US-8207209-B2 | Methods of inhibiting viral infection | FUNCTIONAL GENETICS, INC. (US) | 2012-06-26 | — | — | US | disclosed |
| US-20090170890-A1 | METHOHDS OF INHIBITING VIRAL INFECTION | FUNCTIONAL GENETICS, INC. (US) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170890-A1 | METHOHDS OF INHIBITING VIRAL INFECTION | CASP8, CASP1, CASP3 | NR4A2 4003/4885NCF1 1050/4885HSP90AA1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.