Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199897 | 0.87 | GCK (0.47) | GCKCTSK | |
| SCHEMBL2199899 | 0.87 | GCK (0.47) | GCKCTSK | |
| SCHEMBL15484976 | 0.80 | ALDH1A1 (0.34) | — | |
| SCHEMBL3017123 | 0.80 | GCK (0.48) | GCK | |
| SCHEMBL3017083 | 0.80 | GCK (0.48) | GCK | |
| SCHEMBL2197554 | 0.79 | GCK (0.74) | GCK | |
| SCHEMBL2197550 | 0.79 | GCK (0.74) | GCK | |
| SCHEMBL1711889 | 0.79 | GCK (0.71) | GCK | |
| SCHEMBL1712332 | 0.79 | GCK (0.71) | GCK | |
| SCHEMBL3702379 | 0.77 | GCK (0.46) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029461-A1 | HETEROARYLS AMIDE DERIVATIVES AND THEIR USE AS GLUCOKINASE ACTIVATORS | PFIZER INC. (US) | 2010-03-18 | — | — | WO | disclosed |