Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347598 | 0.88 | GRM5 (0.58) | GRM5DYRK1ACYP17A1CYP11B1 | |
| SCHEMBL3346877 | 0.83 | GRM5 (0.52) | GRM5DYRK1A | |
| SCHEMBL3346922 | 0.82 | GRM5 (0.39) | GRM5DYRK1A | |
| SCHEMBL3347563 | 0.81 | GRM5 (0.36) | GRM5DYRK1ASCN5A | |
| SCHEMBL3347789 | 0.80 | GRM5 (0.49) | GRM5DYRK1ASCN5A | |
| SCHEMBL3347568 | 0.80 | GRM5 (0.38) | GRM5 | |
| SCHEMBL3347295 | 0.80 | GRM5 (0.48) | GRM5DYRK1A | |
| SCHEMBL3346603 | 0.78 | GRM5 (0.41) | GRM5DYRK1ASCN5A | |
| SCHEMBL3347519 | 0.73 | GRM4 (0.46) | GRM5DYRK1A | |
| SCHEMBL3346505 | 0.73 | GRM5 (0.55) | GRM5DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |