Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11907289 | 0.77 | PRKAB2 (0.46) | MAPTFFAR1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2405190 | 0.76 | KDM4E (0.53) | MAPTTSHRPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1711956 | 0.76 | CTSA (0.50) | MAPTFFAR1GRK6DHODHSTIM1 | |
| SCHEMBL1711786 | 0.76 | GRK6 (0.47) | FFAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1965244 | 0.74 | PIN1 (0.54) | MAPTTSHRDHODHKDM4EALDH1A1 | |
| SCHEMBL11907456 | 0.73 | ATR (0.47) | FFAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11909085 | 0.73 | PRKAB2 (0.42) | FFAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL10028262 | 0.72 | KDM4E (0.51) | MAPTTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11906668 | 0.72 | PRKAB2 (0.44) | FFAR1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29939632 | 0.71 | PDE2A (0.44) | MAPTFFAR1GRK6DHODHSTIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |