Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132961 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983600 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL981267 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL493130 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL22288118 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL63140 | 1.00 | — | — | |
| SCHEMBL16114084 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983473 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL982461 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983618 | 1.00 | THRB (0.52) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089515-B2 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2015-07-28 | — | — | US | claimed |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2011-07-28 | — | — | US | claimed |
| US-7786332-B2 | Process for the preparation of ring compounds | MERCK PATENT GMBH (DE) | 2010-08-31 | — | — | US | claimed |
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2010-06-03 | — | — | US | claimed |
| US-7429393-B2 | Graft polymer | BRIDGESTONE CORPORATION (JP) | 2008-09-30 | — | — | US | claimed |
| US-20030130398-A1 | Soft polymeric compounds including metal oxide fillers | BRIDGESTONE CORPORATION | 2003-07-10 | — | — | US | claimed |
| US-20030130426-A1 | Method of grafting polymaleimides to alkenyl butyl rubbers | BRIDGESTONE CORP. | 2003-07-10 | — | — | US | claimed |
| US-20030091527-A1 | Graft polymer | BRIDGESTONE CORPORATION (JP) | 2003-05-15 | — | — | US | claimed |
| WO-2003016398-A1 | THERMOPLASTIC ELASTOMERS AND METHOD OF MAKING THE SAME | BRIDGESTONE CORPORATION (US) | 2003-02-27 | — | — | WO | claimed |
| US-20020188064-A1 | Poly(alkenyl-co-maleimide) , an inorganic salt, and an extender | BRIDGESTONE/FIRESTONE RESEARCH, INC. | 2002-12-12 | — | — | US | claimed |
| WO-2001070822-A2 | PROCESS FOR FORMING CENTIPEDE POLYMER GELS | BRIDGESTONE CORPORATION (JP) | 2001-09-27 | — | — | WO | claimed |
| US-20010021743-A1 | Method of producing a graft copolymer | BRIDGESTONE CORPORATION (JP) | 2001-09-13 | — | — | US | claimed |
| US-6191217-B1 | REACTING POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER WITH MALEATED POLYALKYLENE AND ALKYL DIAMINE UNDER SUBSTANTIALLY DRY CONDITIONS SUFFICIENT TO FORM POLYALKYLENE GRAFTED POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER | BRIDGESTONE CORPORATION (JP) | 2001-02-20 | — | — | US | claimed |
| US-6133354-A | MIXING A POLY(DIALKYLSUBSTITUTED ETHYLENE-CO-MALEIMIDE) POLYMER SUCH AS POLYISOBUTYLENE-CO-MALEIMIDE, AND PLASTICIZERS OR EXTENDERS WITHIN A NON-VULCANIZED THERMOPLASTIC ELASTOMER TO FORM A DAMPING GEL; TENSILE STRENGTH AND TEAR STRENGTH | BRIDGESTONE CORPORATION (JP) | 2000-10-17 | — | — | US | claimed |
| EP-0955319-A1 | Soft compounds derived from polypropylene grafted disubstituted ethylene-maleimide copolymers | Bridgestone Corporation (JP) | 1999-11-10 | — | — | EP | claimed |
| US-5190689-A | Polymer materials having liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | claimed |
| US-4894181-A | Carbocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-01-16 | — | — | US | claimed |
| US-4758373-A | Carbocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-19 | — | — | US | claimed |
| US-4574123-A | BACTERICIDES, FUNGICIDES, STERILIZATION, CONTRACEPTIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-04 | — | — | US | claimed |
| EP-0125091-A2 | 4,4'-Alkylenedipiperidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091527-A1 | Graft polymer | PARG, PARN, PCNA | THRB 4657/4885HTT 2890/4885MEN1 393/4885 |
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | THRB 2907/4885HTT 1700/4885MEN1 3764/4885 |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | THRB 2907/4885HTT 1700/4885MEN1 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.