Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838949 | 0.88 | KMT2A (0.74) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8549452 | 0.86 | KMT2A (0.61) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8747121 | 0.86 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8098121 | 0.86 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL11735352 | 0.85 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7417537 | 0.84 | KMT2A (0.59) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279469 | 0.82 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279475 | 0.82 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL3996984 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1KDM4EMAPT | |
| SCHEMBL3780865 | 0.82 | HDAC1 (0.59) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |