Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417537 | 0.95 | KMT2A (0.59) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7838949 | 0.89 | KMT2A (0.74) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL3351763 | 0.86 | KMT2A (0.60) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8098121 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8747121 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279475 | 0.84 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL7279469 | 0.84 | ALDH1A1 (0.71) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL11735352 | 0.83 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL8928239 | 0.82 | KMT2A (0.65) | KMT2AMEN1ALDH1A1TSHRKDM4E | |
| SCHEMBL10133353 | 0.77 | KMT2A (0.65) | KMT2AMEN1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707570-B1 | ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1998-05-06 | — | — | EP | disclosed |