Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Charcoal, Activated SCHEMBL9341326 | 0.98 | PARP1 (0.40) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL6314578 | 0.98 | PARP1 (0.40) | PARP1KMT2ALMNAMAPTMEN1 | |
| Oxalic Acid SCHEMBL27731733 | 0.95 | HMGB1 (0.38) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL144959 | 0.93 | PARP1 (0.44) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL2964481 | 0.89 | PARP1 (0.45) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL6285466 | 0.86 | CYP3A4 (0.45) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL22736732 | 0.85 | BID (0.48) | KMT2ALMNAMAPTMEN1NR1I2 | |
| Charcoal, Activated SCHEMBL9345982 | 0.85 | CYP3A4 (0.44) | PARP1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL5486335 | 0.84 | KMT2A (0.43) | KMT2ALMNAMAPTMEN1NR1I2 | |
| SCHEMBL8878547 | 0.84 | LTB4R (0.44) | KDM4EALDH1A1HPGDLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084235-A | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | claimed |
| CN-1882544-A | Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer s disease | MERCK & CO INC (US) | 2006-12-20 | — | — | CN | claimed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | claimed |
| EP-1542964-A2 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2005-06-22 | — | — | EP | claimed |
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | claimed |
| WO-2004029019-A2 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-109286041-B | Electrolyte and secondary lithium battery | 宁德时代新能源科技股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-9688618-B2 | Hydroxamic acids and uses thereof | HAWAII BIOTECH, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20170036996-A1 | HYDROXAMIC ACIDS AND USES THEREOF | HAWAII BIOTECH, INC. | 2017-02-09 | — | — | US | disclosed |
| CN-105601551-A | Sulfur-containing hindered phenolic compound as well as preparation and application thereof | CHINA PETROLEUM & CHEM CORP | 2016-05-25 | — | — | CN | disclosed |
| CN-102365280-B | adenosine receptor ligands and uses thereof | DOMAIN THERAPEUTICS (FR) | 2014-10-29 | — | — | CN | disclosed |
| WO-2002048122-A2 | BENZAMIDINE DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-20 | — | — | WO | disclosed |
| CN-1089944-A | The N-Benzanilide derivatives | GLAXO GROUP LTD (GB) | 1994-07-27 | — | — | CN | disclosed |
| US-5306312-A | Dyeing fabric by heating in solution containing dye and aliphatic amide dye diffusion promoter | BURLINGTON INDUSTRIES, INC. (US) | 1994-04-26 | — | — | US | disclosed |
| CN-1071922-A | The N-Benzanilide derivatives | GLAXO GROUP LTD (GB) | 1993-05-12 | — | — | CN | disclosed |
| CN-1016246-B | Process for preparing aminophenol derivatives | GLAXO GROUP LTD (GB) | 1992-04-15 | — | — | CN | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| CN-86102681-A | The preparation method of p-aminophenol derivative and purposes | — | 1987-10-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036996-A1 | HYDROXAMIC ACIDS AND USES THEREOF | HRH3, H1-3, H1-0 | PARP1 855/4885KMT2A 897/4885LMNA 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.