SCHEMBL3352294

SCHEMBL3352294

CC(C)(C)N1CCC(NC(=O)Nc2ccc(C(F)(F)F)cc2)CC1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 19/20 0.73
USP30 Q70CQ3 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1444668 0.87 CXCR3 (0.62) EPHX2
SCHEMBL4010729 0.85 EPHX2 (0.78) EPHX2
SCHEMBL3347934 0.85 EPHX2 (1.00) EPHX2
SCHEMBL20041093 0.84 EPHX2 (0.72) EPHX2USP30
SCHEMBL3346367 0.83 EPHX2 (0.79) EPHX2
SCHEMBL4011037 0.83 EPHX2 (0.79) EPHX2
SCHEMBL4016622 0.83 EPHX2 (0.72) EPHX2USP30
SCHEMBL4997818 0.83 EPHX2 (0.79) EPHX2
SCHEMBL4009460 0.82 EPHX2 (0.78) EPHX2
SCHEMBL2717167 0.82 EPHX2 (1.00) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010053829-A1 SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR TREATMENT OF METABOLIC SYNDROME AND RELATED DISORDERS ARETE THERAPEUTICS, INC. (US) 2010-05-14 WO disclosed