SCHEMBL33525683

SCHEMBL33525683

Cc1ccc(S(=O)(=O)n2ccc3c2C(=O)N(C)CC3Br)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
POLB P06746 2/20 0.39
HTT P42858 2/20 0.39
ALDH3A1 P30838 1/20 0.39
NOD1 Q9Y239 1/20 0.39
MMP2 P08253 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
RAPGEF4 Q8WZA2 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
PKM P14618 2/20 0.36
GAA P10253 1/20 0.36
ACHE P22303 1/20 0.36
HSD11B1 P28845 1/20 0.36
HTR6 P50406 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10854578 0.66 MMP2 (0.42) L3MBTL1MCOLN3POLBHTTMMP2
SCHEMBL3621840 0.64 PKM (0.51) POLBHTTMMP2PKMGAA
SCHEMBL14726921 0.64 MMP2 (0.43) L3MBTL1POLBHTTMMP2CA1
SCHEMBL30990322 0.64 PKM (0.43) L3MBTL1POLBHTTALDH3A1NOD1
SCHEMBL3579224 0.64 PKM (0.59) POLBHTTPKMGAAALDH1A1
SCHEMBL30990289 0.63 ELANE (0.45) L3MBTL1POLBHTTALDH3A1NOD1
SCHEMBL18951957 0.63 CA1 (0.53) L3MBTL1POLBHTTALDH3A1NOD1
SCHEMBL29001261 0.63 CA1 (0.59) L3MBTL1POLBHTTALDH3A1NOD1
SCHEMBL21045977 0.62 CA1 (0.40) L3MBTL1POLBHTTALDH3A1NOD1
SCHEMBL16382709 0.62 CA1 (0.53) L3MBTL1POLBHTTALDH3A1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092065-A1 CRYSTALLINE SOLID FORMS OF A BET INHIBITOR INCYTE CORP (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092065-A1 CRYSTALLINE SOLID FORMS OF A BET INHIBITOR BRD2, BRDT, BRD1 L3MBTL1 632/4885MCOLN3 1061/4885POLB 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.