SCHEMBL33525760

SCHEMBL33525760

COc1nc(Cl)c(Cl)cc1C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.49
GAA P10253 1/20 0.46
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
POLB P06746 2/20 0.40
HPGD P15428 1/20 0.39
RECQL P46063 1/20 0.39
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.36
ADRB2 P07550 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232391 0.76 KHK (0.52) GAAKDM4EALDH1A1TDP1POLB
SCHEMBL566195 0.76 KHK (0.52) GAAKDM4EALDH1A1TDP1POLB
SCHEMBL31254099 0.76 TDP1 (0.58) L3MBTL1MEN1KMT2AALDH1A1TDP1
SCHEMBL11749341 0.76 TDP1 (0.58) L3MBTL1MEN1KMT2AALDH1A1TDP1
SCHEMBL6186446 0.75 KHK (0.57) L3MBTL1GAAKDM4EMEN1KMT2A
SCHEMBL565839 0.75 PDE4A (0.56) L3MBTL1GAAKDM4EMEN1KMT2A
SCHEMBL11387117 0.75 NPSR1 (0.49) L3MBTL1GAAKDM4EALDH1A1TDP1
SCHEMBL565703 0.74 PDE4B (0.54) L3MBTL1GAAKDM4ETDP1HPGD
SCHEMBL566051 0.72 PDE4B (0.57) KDM4ETDP1HPGDCNR1CNR2
SCHEMBL30656267 0.72 KDM4E (0.55) L3MBTL1GAAKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 L3MBTL1 3664/4885GAA 2113/4885KDM4E 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.