Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12682543 | 0.84 | KDM4E (0.51) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL25962879 | 0.84 | KDM4E (0.51) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL30656367 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL25962880 | 0.80 | KDM4E (0.48) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL27883168 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL30656058 | 0.74 | ADORA1 (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL810713 | 0.74 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL12682611 | 0.73 | KDM4E (0.54) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL23860814 | 0.73 | KHK (0.49) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL33525760 | 0.72 | L3MBTL1 (0.49) | KDM4EPOLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119136802-A | Adenosine 2A receptor modulators for the treatment of cancer | 瑞士日内瓦大学 | 2024-12-13 | — | — | CN | claimed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | claimed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | claimed |
| CN-119136802-A | Adenosine 2A receptor modulators for the treatment of cancer | 瑞士日内瓦大学 | 2024-12-13 | — | — | CN | disclosed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |