SCHEMBL33526224

SCHEMBL33526224

Cn1nc(F)c2ncc(Br)cc21

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
DYRK1A Q13627 1/20 0.32
PDE1B Q01064 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
PAK4 O96013 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30506328 0.80 HSD17B10 (0.43) HSD17B10KDM4EALDH1A1HRH4HRH3
SCHEMBL17674371 0.80 HSD17B10 (0.43) HSD17B10KDM4EALDH1A1HRH4HRH3
SCHEMBL30791898 0.79 HSD17B10 (0.42) HSD17B10KDM4EALDH1A1DYRK1APDE1B
SCHEMBL26621529 0.79 HSD17B10 (0.42) HSD17B10KDM4EALDH1A1DYRK1APDE1B
SCHEMBL30385415 0.79 HTT (0.42) HSD17B10KDM4EALDH1A1DYRK1APDE1B
SCHEMBL20741029 0.79 HSD17B10 (0.42) HSD17B10KDM4EALDH1A1DYRK1APDE1B
SCHEMBL27259688 0.78 KDM4E (0.43) HSD17B10KDM4EALDH1A1DYRK1AHTT
SCHEMBL30224197 0.72 GRIN1 (0.35) HSD17B10
SCHEMBL33526579 0.72 HRH4 (0.35) KDM4EALDH1A1HRH4
SCHEMBL33526125 0.71 ALOX15 (0.31) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 HSD17B10 1101/4885KDM4E 2674/4885ALDH1A1 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.