⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8506704 | 0.97 | — | — | |
| Benzene SCHEMBL28152864 | 0.95 | KMT2A (0.49) | — | |
| SCHEMBL28879071 | 0.89 | KMT2A (0.43) | — | |
| SCHEMBL28230886 | 0.89 | CYP1A2 (0.42) | — | |
| Pyridine SCHEMBL28144117 | 0.85 | ALDH1A1 (0.42) | — | |
| Toluene SCHEMBL28651188 | 0.82 | L3MBTL1 (0.48) | — | |
| Bicarbonate SCHEMBL28049114 | 0.82 | SMN1; SMN2 (0.44) | — | |
| Hydrochlorthiazide SCHEMBL28331705 | 0.81 | CYP1A2 (0.37) | — | |
| SCHEMBL28901989 | 0.80 | — | — | |
| SCHEMBL28407528 | 0.78 | PDCD1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974866-B | Synthesis method of thiamethoxam | 河北德瑞化工有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-119019385-A | Novel thiazide method for synthesizing chlorphenamine maleate | 宁夏农加新材料科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118745160-A | Clean and environment-friendly preparation method of 2-chloro-5-chloromethylthiazole | 河北中天实业有限公司 | 2024-10-08 | — | — | CN | claimed |
| CN-116082271-B | Method for preparing 2-chloro-5-chloromethylthiazole by one-step method | 济宁福顺化工有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-116200174-B | Preparation method and application of sulfur-nitrogen extreme pressure lubricant for drilling fluid | 西南石油大学 | 2024-09-13 | — | — | CN | claimed |
| CN-116102517-B | Synthesis method of 2-chloro-5-chloromethylthiazole | 郑州大学 | 2024-09-10 | — | — | CN | claimed |
| CN-221579730-U | 2-Chloro-5-chloromethylthiazole production processing purification separator | 河北中天实业有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-115785020-B | Synthesis method of 2-chloro-5-chloromethylthiazole | 济宁福顺化工有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-220736239-U | Recycling system for extracting hydrochloric acid by using 2-chloro-5-chloromethylthiazole | 山西玉龙化工有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117815613-A | Method for residual curing of 2-chloro-5-chloromethylthiazole kettle | 河北德瑞化工有限公司 | 2024-04-05 | — | — | CN | claimed |
| EP-0780384-A2 | Process for the production of 2-chloro-5-chloromethylthiazole | BAYER AG (DE) | 1997-06-25 | — | — | EP | claimed |
| EP-0446913-B1 | Process for the preparation of chlorothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | EP | claimed |
| EP-0775700-A1 | Process for the replacement of a primary amino group by a chlorine atom and utilization of this process for the preparation of 2-chloro-5-chloromethyl-thiazol | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-05-28 | — | — | EP | claimed |
| WO-1996016050-A1 | PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE | ABBOTT LABORATORIES (US) | 1996-05-30 | — | — | WO | claimed |
| US-5461167-A | 2-chloro-5-chloromethyl thiazole; insecticide | NIHON BAYER AGROCHEM K.K. (JP) | 1995-10-24 | — | — | US | claimed |
| US-5180833-A | PROCESS FOR THE PREPARATION OF CHLOROTHIAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | claimed |
| EP-0446913-A1 | Process for the preparation of chlorothiazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | claimed |
| EP-0260560-B1 | PROCESS FOR THE PREPARATION OF 2-CHLOR-5-CHLORMETHYL THIAZOLE | BAYER AG (DE) | 1990-05-16 | — | — | EP | claimed |
| US-4748243-A | Preparation of 2-chloro-5-chloromethylthiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | claimed |
| EP-0260560-A1 | Process for the preparation of 2-chlor-5-chlormethyl thiazole | BAYER AG (DE) | 1988-03-23 | — | — | EP | claimed |