SCHEMBL33527391

SCHEMBL33527391

COc1ccc2c(c1)Cc1c(C)cccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
METAP1 P53582 2/20 0.47
EIF2AK1 Q9BQI3 2/20 0.46
ACHE P22303 3/20 0.45
MAOB P27338 2/20 0.43
PDGFRB P09619 1/20 0.43
CYP26A1 O43174 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
BACE1 P56817 2/20 0.42
DRD2 P14416 3/20 0.41
DRD1 P21728 3/20 0.41
DRD5 P21918 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26780002 1.00 CA1 (0.50) CA1CA2CA4CA6METAP1
SCHEMBL7168538 0.84 METAP1 (0.46) CA1CA2CA4CA6METAP1
SCHEMBL29432302 0.80 MAPT (0.45) METAP1ACHECYP1A2ALDH1A1CYP2A6
SCHEMBL601330 0.80 MAPT (0.45) METAP1ACHECYP1A2ALDH1A1CYP2A6
SCHEMBL4581239 0.78 METAP1 (0.63) CA1CA2CA4CA6METAP1
SCHEMBL30777630 0.78 METAP1 (0.63) CA1CA2CA4CA6METAP1
SCHEMBL2914928 0.78 DRD1 (0.58) CA1CA2CA4CA6METAP1
SCHEMBL29633762 0.78 DRD1 (0.58) CA1CA2CA4CA6METAP1
SCHEMBL28941745 0.77 HSP90AA1 (0.59) CA1CA2CA4CA6METAP1
SCHEMBL26780005 0.77 TYR (0.48) CA1CA2CA4CA6MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES DYRK1B, DYRK2, DYRK4 CA1 2237/4885CA2 1473/4885CA4 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.