Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.58 |
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | DRD5 | P21918 | 7/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914928 | 1.00 | DRD1 (0.58) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL3287680 | 0.92 | ALDH1A1 (0.56) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL10692678 | 0.91 | METAP1 (0.63) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL30777630 | 0.90 | METAP1 (0.63) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL4581239 | 0.90 | METAP1 (0.63) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL10623445 | 0.86 | ALDH1A1 (0.64) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL1480944 | 0.86 | ALDH1A1 (0.56) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL6900363 | 0.86 | DRD1 (0.74) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL14007350 | 0.84 | ALDH1A1 (0.61) | DRD1DRD2DRD5DRD3DRD4 | |
| SCHEMBL7040518 | 0.83 | DRD1 (0.57) | DRD1DRD2DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103983-A9 | FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022103983-A2 | FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2022-05-19 | — | — | WO | disclosed |