Sugi Predict

Sugi Predict / Compounds / SCHEMBL2914928

SCHEMBL2914928

SCHEMBL2914928

COc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD1 P21728 8/20 0.58
▸ DRD2 P14416 7/20 0.58
▸ DRD5 P21918 7/20 0.58
▸ DRD3 P35462 7/20 0.58
▸ DRD4 P21917 5/20 0.58
▸ ALDH1A1 P00352 5/20 0.57
▸ MAPT P10636 4/20 0.57
▸ KDM4E B2RXH2 3/20 0.57
▸ HPGD P15428 3/20 0.57
▸ SMN1; SMN2 Q16637 3/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ CYP2C9 P11712 2/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ TP53 P04637 1/20 0.56
▸ CYP2D6 P10635 1/20 0.56
▸ PKM P14618 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ MAPK1 P28482 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ METAP1 P53582 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633762 1.00 DRD1 (0.58) DRD1DRD2DRD5DRD3DRD4
SCHEMBL3287680 0.92 ALDH1A1 (0.56) DRD1DRD2DRD5DRD3DRD4
SCHEMBL10692678 0.91 METAP1 (0.63) DRD1DRD2DRD5DRD3DRD4
SCHEMBL30777630 0.90 METAP1 (0.63) DRD1DRD2DRD5DRD3DRD4
SCHEMBL4581239 0.90 METAP1 (0.63) DRD1DRD2DRD5DRD3DRD4
SCHEMBL10623445 0.86 ALDH1A1 (0.64) DRD1DRD2DRD5DRD3DRD4
SCHEMBL1480944 0.86 ALDH1A1 (0.56) DRD1DRD2DRD5DRD3DRD4
SCHEMBL6900363 0.86 DRD1 (0.74) DRD1DRD2DRD5DRD3DRD4
SCHEMBL14007350 0.84 ALDH1A1 (0.61) DRD1DRD2DRD5DRD3DRD4
SCHEMBL7040518 0.83 DRD1 (0.57) DRD1DRD2DRD5DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128458-A A kind of preparation method of 9,9- dimethyl fluorene 2- methoxyl group -3- boric acid 浙江京合信新材料科技有限公司 2019-08-16 — — CN claimed
US-20260092214-A1 POLYMERIZABLE COMPOUND AND USE THEREOF BEIJING BAYI SPACE LCD TECH CO LTD (CN) 2026-04-02 — — US disclosed
WO-2024260293-A1 POLYMERIZABLE COMPOUND AND USE THEREOF 北京八亿时空液晶科技股份有限公司 2024-12-26 — — WO disclosed
CN-119176751-A Polymerizable compound and application thereof 北京八亿时空液晶科技股份有限公司 2024-12-24 — — CN disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
CN-116462579-B Preparation method of spirofluorene anthrone compound 大连理工大学 2024-04-05 — — CN disclosed
CN-115521195-B Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2024-01-26 — — CN disclosed
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-25 — — US disclosed
US-20230329086-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 — — US disclosed
CN-116462579-A Preparation method of spirofluorene anthrone compound 大连理工大学 2023-07-21 — — CN disclosed
EP-0709393-A2 Olefin polymerization catalyst and process for producing olefin polymer TOSOH CORPORATION (JP) 1996-05-01 — — EP disclosed
US-5434264-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-07-18 — — US disclosed
US-5300642-A α, α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-04-05 — — US disclosed
EP-0311010-B1 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers DU PONT MERCK PHARMA (US) 1994-02-02 — — EP disclosed
EP-0531443-A4 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN — 1993-04-21 — — EP disclosed
EP-0532054-A1 Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 — — EP disclosed
EP-0531443-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN NOVA PHARMACEUTICAL CORPORATION (US) 1993-03-17 — — EP disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 — — US disclosed
US-5079260-A Side effect reduction; fluorene derivatives NOVA PHARMACEUTICAL CORPORATION (US) 1992-01-07 — — US disclosed
WO-1991018596-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN WEITZBERG MOSHE (US) 1991-12-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032415-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LAGE3, CRY1, LEF1 DRD1 1064/4885DRD2 2315/4885DRD5 3959/4885
US-20260092214-A1 POLYMERIZABLE COMPOUND AND USE THEREOF CCNL2, CCND2, CCND1 DRD1 1459/4885DRD2 1250/4885DRD5 2896/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG DRD1 83/4885DRD2 47/4885DRD5 198/4885
US-20230329086-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME LAGE3, LEF1, EML4 DRD1 1479/4885DRD2 2658/4885DRD5 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.