SCHEMBL33527568

SCHEMBL33527568

Cc1c(C#N)cc(F)c[n+]1[O-]

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.31
TRPV4 Q9HBA0 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13844293 0.73
SCHEMBL2085147 0.73
SCHEMBL17570611 0.68 TRPV4 (0.38) TRPV4MAOAMAOB
SCHEMBL27585332 0.64 TSHR (0.45)
SCHEMBL5990340 0.63 TSHR (0.34)
SCHEMBL101523 0.63 TSHR (0.48) TRPV4MAOAMAOB
SCHEMBL20562679 0.63 TSHR (0.38) TRPV4
SCHEMBL16481702 0.63 TSHR (0.38) TRPV4
SCHEMBL13525263 0.63 DHODH (0.40) TRPV4
SCHEMBL30283688 0.63 TSHR (0.48) TRPV4MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 PTGS2 2150/4885TRPV4 607/4885MAOA 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.