SCHEMBL3352759

SCHEMBL3352759

O=S(=O)(O)CC1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
INPP5A Q14642 1/20 0.47
CNR2 P34972 4/20 0.32
CNR1 P21554 2/20 0.32
AOC2 O75106 2/20 0.32
MAOA P21397 1/20 0.32
KCNH2 Q12809 1/20 0.31
AKT1 P31749 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
GBA1 P04062 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23012533 0.86 INPP5A (0.44) INPP5AAOC2MAOAAKT1PIK3CA
SCHEMBL1647665 0.86 INPP5A (0.44) INPP5AAOC2MAOAAKT1PIK3CA
SCHEMBL23160212 0.86 INPP5A (0.44) INPP5AAOC2MAOAAKT1PIK3CA
SCHEMBL6962289 0.85 INPP5A (0.42) INPP5AAOC2MAOAAKT1PIK3CA
SCHEMBL7931443 0.82
SCHEMBL9099973 0.82 INPP5A (0.62) INPP5A
Hydrochloric Acid SCHEMBL27888894 0.79
SCHEMBL965787 0.79
SCHEMBL27984591 0.78 INPP5A (0.38) INPP5AAOC2MAOAAKT1PIK3CA
SCHEMBL2573293 0.77 APP (0.34) INPP5ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930958-A Anion exchange polymer and preparation method thereof, and preparation method of anion exchange membrane 惠州亿纬氢能有限公司 2025-05-06 CN claimed
CN-121045118-A Synthesis method of tetrahydropyran-4-sulfonyl chloride 常熟泓德生物科技有限公司 2025-12-02 CN disclosed
CN-116507333-B Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use 上海睿跃生物科技有限公司 2025-05-09 CN disclosed
CN-119930958-A Anion exchange polymer and preparation method thereof, and preparation method of anion exchange membrane 惠州亿纬氢能有限公司 2025-05-06 CN disclosed
CN-119775277-A Compounds as modulators of LRRK2, NUAK1 and/or TYK2 kinases for the treatment of, for example, autoimmune diseases 原真股份有限公司 2025-04-08 CN disclosed
CN-119585252-A Bicyclic heteroaryl containing compounds as IKZF2 degrading agents 翁科皮亚治疗公司和SK生命科学实验室 2025-03-07 CN disclosed
CN-119562952-A KIF18A inhibitors 山东轩竹医药科技有限公司 2025-03-04 CN disclosed
CN-119330963-A Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use 上海睿跃生物科技有限公司 2025-01-21 CN disclosed
CN-119118999-A Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof 凌科药业(杭州)有限公司 2024-12-13 CN disclosed
CN-118955477-A Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof 凌科药业(杭州)有限公司 2024-11-15 CN disclosed
WO-2022092141-A1 AMIDE DERIVATIVE HAVING ANTIVIRAL ACTIVITY 塩野義製薬株式会社 2022-05-05 WO disclosed
CN-113227074-A Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods 凌科药业(杭州)有限公司 2021-08-06 CN disclosed
CN-107849017-B 1,1, 1-trifluoro-3-hydroxypropan-2-ylcarbamate derivatives and 1,1, 1-trifluoro-4-hydroxybutyl-2-ylcarbamate derivatives as MAGL inhibitors 辉瑞公司 2021-03-30 CN disclosed
CN-112409334-A Novel heterocyclic derivatives useful as SHP2 inhibitors 北京加科思新药研发有限公司 2021-02-26 CN disclosed
CN-112174935-A Novel heterocyclic derivatives useful as SHP2 inhibitors 北京加科思新药研发有限公司 2021-01-05 CN disclosed
CN-111433208-A Pyrrolo (pyrazolo) pyrimidine derivatives as L RRK2 inhibitors 奥斯考泰克公司 2020-07-17 CN disclosed
US-10233176-B2 Aminopyridine derivatives as TAM family kinase inhibitors SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2019-03-19 US disclosed
WO-2018103060-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE JANSSEN PHARMACEUTICA NV (BE) 2018-06-14 WO disclosed
US-20170022189-A1 AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2017-01-26 US disclosed
EP-2141163-A1 Substituted thiazolidinones, their production and utilisation as medicine Bayer Schering Pharma AG (DE) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233176-B2 Aminopyridine derivatives as TAM family kinase inhibitors MAP3K6, MAP3K5, MERTK INPP5A 2868/4885CNR2 2982/4885CNR1 3339/4885
US-20170022189-A1 AMINOPYRIDINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS MAP3K6, MAP3K5, MERTK INPP5A 2868/4885CNR2 2982/4885CNR1 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.