Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962289 | 0.93 | INPP5A (0.42) | INPP5AAOC2MAOAAKT1PIK3CA | |
| SCHEMBL23160212 | 0.91 | INPP5A (0.44) | INPP5AAOC2MAOAAKT1PIK3CA | |
| SCHEMBL1647665 | 0.91 | INPP5A (0.44) | INPP5AAOC2MAOAAKT1PIK3CA | |
| SCHEMBL23012533 | 0.91 | INPP5A (0.44) | INPP5AAOC2MAOAAKT1PIK3CA | |
| SCHEMBL26695944 | 0.79 | INPP5A (0.41) | INPP5AAOC2MAOA | |
| SCHEMBL3352759 | 0.78 | INPP5A (0.47) | INPP5AAOC2MAOAAKT1PIK3CA | |
| SCHEMBL25292677 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL4771641 | 0.75 | AOC2 (0.38) | AOC2MAOAAKT1PIK3CAMTOR | |
| SCHEMBL15732885 | 0.74 | — | — | |
| SCHEMBL158873 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507921-A | Benzocyclobutene derivative and preparation method and pharmaceutical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |