Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265180 | 0.92 | HTR7 (0.56) | HTR7MAPTKMT2AMTNR1AMTNR1B | |
| SCHEMBL30672858 | 0.89 | PLG (0.46) | HTR7KMT2AF2RL3 | |
| SCHEMBL2124040 | 0.89 | PLG (0.46) | HTR7KMT2AF2RL3 | |
| SCHEMBL27732822 | 0.84 | HTR7 (0.54) | HTR7MAPTKMT2AMTNR1AMTNR1B | |
| SCHEMBL15712293 | 0.84 | HTR7 (0.62) | HTR7MAPTKMT2AMTNR1AMTNR1B | |
| SCHEMBL17023236 | 0.82 | HTR7 (0.59) | HTR7MAPTIRAK4MTNR1AMTNR1B | |
| SCHEMBL2872712 | 0.82 | HTR7 (0.57) | HTR7MAPTIRAK4KMT2AMTNR1A | |
| SCHEMBL4511606 | 0.81 | HTR7 (0.51) | HTR7MAPTMTNR1AMTNR1BCDC7 | |
| SCHEMBL1122380 | 0.81 | HTR7 (0.58) | HTR7MAPTIRAK4MTNR1AMTNR1B | |
| SCHEMBL3312100 | 0.81 | HTR7 (0.57) | HTR7MAPTKMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |