Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430045 | 0.88 | SMN1; SMN2 (0.50) | MEN1KMT2AKDM4EMAPK1MCHR1 | |
| SCHEMBL30782239 | 0.83 | KDM2B (0.51) | HSD17B10MCHR1HPGDHDAC1F10 | |
| SCHEMBL9039147 | 0.82 | NPC1 (0.50) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL29738011 | 0.82 | MEN1 (0.54) | MEN1KMT2APTGER4NPC1RAB9A | |
| SCHEMBL6799725 | 0.81 | NPC1 (0.49) | KCNH2HRH3NPC1RAB9AKDM4E | |
| SCHEMBL25998805 | 0.81 | SIRT2 (0.49) | NPC1RAB9AKDM4EHPGDALDH1A1 | |
| SCHEMBL4916141 | 0.81 | NPC1 (0.48) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL24233569 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL24075008 | 0.79 | HPGD (0.49) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL17678353 | 0.78 | TSHR (0.48) | KCNH2HRH3HSD17B10MCHR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |