Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354874 | 0.85 | KDM4E (0.54) | ALDH1A1MAPTKDM4ENSD2MEN1 | |
| SCHEMBL15910937 | 0.82 | KDM4E (0.51) | ALDH1A1MAPTKDM4ENSD2MEN1 | |
| SCHEMBL3351305 | 0.82 | MAPT (0.47) | ALDH1A1MAPTKDM4ENSD2KMT2A | |
| SCHEMBL13537243 | 0.81 | KDM5A (0.37) | KDM5AGSK3BDYRK1AHRH3CLK2 | |
| SCHEMBL3357865 | 0.79 | MAPT (0.52) | ALDH1A1MAPTKDM4EKDM5AMEN1 | |
| SCHEMBL26684343 | 0.78 | KDM4E (0.42) | ALDH1A1MAPTKDM4ENSD2KDM5A | |
| SCHEMBL30508322 | 0.76 | TLR8 (0.40) | ALDH1A1MAPTNSD2KDM5ANPC1 | |
| SCHEMBL2265239 | 0.76 | TLR8 (0.40) | KDM5AGSK3BDYRK1AHRH3MAPK14 | |
| SCHEMBL25338952 | 0.74 | NR1H2 (0.46) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL22041254 | 0.72 | KDM5A (0.38) | ALDH1A1MAPTKDM4ENSD2KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |