Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334843 | 0.94 | KDR (0.45) | F9F7F11KDRNPC1 | |
| SCHEMBL335390 | 0.92 | ABL1 (0.44) | F9F7F11L3MBTL1NPC1 | |
| SCHEMBL336071 | 0.89 | PYGL (0.45) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL335308 | 0.89 | MEN1 (0.44) | KDRL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL336586 | 0.88 | GRIN1 (0.44) | F9F7KDRABL1FABP6 | |
| SCHEMBL335498 | 0.88 | TAS1R3 (0.45) | F9F7F11L3MBTL1NPC1 | |
| SCHEMBL335420 | 0.88 | NPC1 (0.46) | F9F7F11NPC1RAB9A | |
| SCHEMBL336155 | 0.87 | TAS1R3 (0.45) | KDRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL335396 | 0.87 | F7 (0.44) | F9F7L3MBTL1NPC1RAB9A | |
| SCHEMBL336367 | 0.86 | MAPT (0.47) | F9F7L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |