SCHEMBL335391

SCHEMBL335391

O=C(CCCC1CO1)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.53
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
EPHX2 P34913 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334225 0.96 MGLL (0.54) MGLLALDH1A1MAPK1L3MBTL1EPHX2
SCHEMBL27312109 0.94 MGLL (0.55) MGLLALDH1A1MAPK1L3MBTL1EPHX2
SCHEMBL335071 0.91 ALDH1A1 (0.53) MGLLALDH1A1MAPK1L3MBTL1
SCHEMBL27312116 0.85 MGLL (0.49) MGLLALDH1A1MAPK1L3MBTL1EPHX2
SCHEMBL334732 0.81 ALDH1A1 (0.56) MGLLALDH1A1MAPK1L3MBTL1MEN1
SCHEMBL21768202 0.81 MAPT (0.44) MGLLALDH1A1MAPK1L3MBTL1
SCHEMBL18673 0.81 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1EPHX2MEN1
SCHEMBL3963428 0.81 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1EPHX2MEN1
SCHEMBL334237 0.79 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1EPHX2MEN1
SCHEMBL20624816 0.79 ALDH1A1 (0.66) MGLLALDH1A1MAPK1L3MBTL1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030987-B2 Aliphatic polycarbonate SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2024-07-09 US disclosed
US-12030987-B2 Aliphatic polycarbonate SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2024-07-09 US disclosed
US-20220098364-A1 ALIPHATIC POLYCARBONATE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2022-03-31 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
EP-1985620-A1 10a-AZALIDE COMPOUND TAISHO PHARMACEUTICAL CO., LTD (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 MGLL 1506/4885ALDH1A1 1939/4885MAPK1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.