SCHEMBL3353992

SCHEMBL3353992

C=CCSc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.66
ALDH1A1 P00352 6/20 0.66
MAPK1 P28482 2/20 0.66
TSHR P16473 1/20 0.66
HRH3 Q9Y5N1 1/20 0.43
FKBP1A P62942 3/20 0.40
RAB9A P51151 2/20 0.40
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
MAPT P10636 2/20 0.35
PKM P14618 1/20 0.35
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
MLYCD O95822 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023887 0.89 SMN1; SMN2 (0.52) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10886078 0.85 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10883782 0.85 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL6674533 0.84 SMN1; SMN2 (0.72) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL8900827 0.84 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL26785899 0.84 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10886640 0.84 ALDH1A1 (0.81) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL278825 0.83 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL26785901 0.83 ALDH1A1 (0.71) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10887287 0.83 SMN1; SMN2 (0.75) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5667541-A BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US claimed
EP-0232422-A1 TRANSPARENT CONDUCTIVE FILM INTEGRATED WITH POLARIZING MEMBRANE SUMITOMO BAKELITE COMPANY LIMITED (JP) 1987-08-19 EP claimed
JP-10114736-A None JP disclosed
JP-10114736-A None JP disclosed
US-20230104836-A1 TRANSFER FILM AND METHOD FOR PRODUCING LAMINATE FUJIFILM CORPORATION (JP) 2023-04-06 US disclosed
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2049172-B1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST AS (DK) 2014-12-31 EP disclosed
JP-H10114736-A PRODUCTION OF 2-METHYL-1-(4-(ALKYLTHIO)PHENYL)-2-MORPHOLINO-1-PROPANONE SUMITOMO SEIKA CHEM CO LTD 1998-05-06 JP disclosed
JP-H10114736-A PRODUCTION OF 2-METHYL-1-(4-(ALKYLTHIO)PHENYL)-2-MORPHOLINO-1-PROPANONE SUMITOMO SEIKA CHEM CO LTD 1998-05-06 JP disclosed
US-5667541-A BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
EP-0654323-A1 Coatable compositions, abrasive articles made therefrom, and methods of making and using same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-24 EP disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4774141-A Polarizing film-integrated transparent electrically conductive film SUMITOMO BAKELITE COMPANY LIMITED (JP) 1988-09-27 US disclosed
EP-0232422-A1 TRANSPARENT CONDUCTIVE FILM INTEGRATED WITH POLARIZING MEMBRANE SUMITOMO BAKELITE COMPANY LIMITED (JP) 1987-08-19 EP disclosed
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed