SCHEMBL3354148

SCHEMBL3354148

CCOC(OCC)[SiH2]CN1CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
SIGMAR1 Q99720 3/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502896 0.82
SCHEMBL30493979 0.81 MEN1 (0.31)
SCHEMBL2501932 0.81 MEN1 (0.31)
SCHEMBL28982413 0.81 SMN1; SMN2 (0.35) SMN1; SMN2SIGMAR1CHRM5CHRM3
SCHEMBL31468475 0.79 KDM4E (0.31)
SCHEMBL29014882 0.78 POLB (0.33)
SCHEMBL2413668 0.78 USP2 (0.35) SMN1; SMN2SIGMAR1
SCHEMBL3708780 0.74 GNAI3 (0.40)
SCHEMBL11268764 0.71 SMN1; SMN2 (0.47) SMN1; SMN2SIGMAR1CHRM5CHRM3
SCHEMBL3702868 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947750-A Carboxylated silane coupling agent and preparation method thereof 山东东岳有机硅材料股份有限公司 2023-04-11 CN disclosed
CN-115819448-A Synthetic method of nitrogen-containing six-membered ring functionalized alpha silane coupling agent in self-heat-release system 山东东岳有机硅材料股份有限公司 2023-03-21 CN disclosed
US-20100010166-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2010-01-14 US disclosed
EP-2064256-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2009-06-03 EP disclosed
WO-2008031895-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2008-03-20 WO disclosed