SCHEMBL3708780

SCHEMBL3708780

CCOC(OCC)[SiH2]CNN1CCNCC1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707782 0.83 GNAI3 (0.39) GNAI3GNAO1GNAI1
SCHEMBL3703408 0.80 TSHR (0.32)
SCHEMBL3354148 0.74 SMN1; SMN2 (0.37)
SCHEMBL935161 0.74 GNAI3 (0.43) GNAI3GNAO1GNAI1
Piperazine SCHEMBL28971410 0.68 THRB (0.33)
SCHEMBL555286 0.67 THRB (0.36)
SCHEMBL1537342 0.67
SCHEMBL3702868 0.67
Hydrochloric Acid SCHEMBL6096892 0.65 GNAI3 (0.59) GNAI3GNAO1GNAI1
Bromide SCHEMBL28768421 0.65 GNAI3 (0.53) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed