Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355141 | 0.83 | JAK2 (0.49) | JAK2JAK1 | |
| SCHEMBL2798597 | 0.83 | ALDH1A1 (0.43) | ALDH1A1FPR2PROKR1PRKAA2 | |
| SCHEMBL5811202 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL18321618 | 0.78 | NPSR1 (0.41) | ALDH1A1FPR2PROKR1CYP2D6 | |
| SCHEMBL3352880 | 0.77 | KDM1A (0.33) | FPR2PROKR1TSHRCYP2D6KDM1A | |
| SCHEMBL23647559 | 0.72 | CYP46A1 (0.44) | ALDH1A1JAK2JAK1TSHR | |
| SCHEMBL3116168 | 0.72 | MEN1 (0.53) | PRKAA2MEN1KMT2A | |
| SCHEMBL28123143 | 0.72 | CHRM2 (0.46) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22719293 | 0.71 | MGLL (0.43) | JAK2JAK1 | |
| SCHEMBL18321417 | 0.71 | ESR2 (0.42) | FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |