Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353782 | 0.89 | ALDH1A1 (0.42) | HTR3EHTR3BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13537408 | 0.86 | KDM4C (0.42) | SLC6A4SLC6A2KDM4C | |
| SCHEMBL31735651 | 0.86 | CHRNB4 (0.44) | HTR3EHTR3BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3354240 | 0.83 | HTR7 (0.45) | ALDH1A1SLC6A4SLC6A2SIRT6 | |
| SCHEMBL29263697 | 0.81 | SLC6A2 (0.44) | ALDH1A1CYP1A2SLC6A2SIRT2KRAS | |
| SCHEMBL31036118 | 0.81 | SLC6A2 (0.44) | ALDH1A1CYP1A2SLC6A2SIRT2KRAS | |
| SCHEMBL23902708 | 0.81 | SLC6A2 (0.40) | ALDH1A1SLC6A2SIRT2KRASADRA2A | |
| SCHEMBL1865868 | 0.80 | KRAS (0.41) | ALDH1A1CYP1A2SLC6A2KRAS | |
| SCHEMBL13537503 | 0.80 | MEN1 (0.42) | ALDH1A1SLC6A4SLC6A2SIRT2KRAS | |
| SCHEMBL31735701 | 0.80 | SLC6A2 (0.43) | ALDH1A1CYP1A2SLC6A2SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |