Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358873 | 0.84 | MAPT (0.59) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL25256131 | 0.81 | TLR8 (0.46) | MAPTTLR8TLR4TLR9TLR7 | |
| SCHEMBL3354814 | 0.81 | MAPT (0.52) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3357865 | 0.81 | MAPT (0.52) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL15910847 | 0.77 | MAPT (0.43) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3352407 | 0.77 | MAPT (0.50) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29082025 | 0.77 | TLR8 (0.48) | TLR8TLR4TLR9TLR7IRAK4 | |
| SCHEMBL13537310 | 0.76 | TLR8 (0.48) | TLR8TLR4TLR9TLR7IRAK4 | |
| SCHEMBL30291044 | 0.75 | TLR8 (0.43) | TLR8TLR4TLR9TLR7IRAK4 | |
| SCHEMBL20809468 | 0.73 | TLR8 (0.52) | MEN1KMT2ATLR8ALDH1A1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |