Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358873 | 0.87 | MAPT (0.59) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3357865 | 0.84 | MAPT (0.52) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3354928 | 0.81 | MAPT (0.53) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3351305 | 0.79 | MAPT (0.47) | MAPTKMT2ASMN1; SMN2ALDH1A1DRD4 | |
| SCHEMBL13537595 | 0.79 | MET (0.36) | KMT2ADRD4 | |
| SCHEMBL3352407 | 0.78 | MAPT (0.50) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3352833 | 0.74 | MAPT (0.45) | MAPTKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL18896263 | 0.74 | MAPT (0.66) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3358021 | 0.74 | HTR7 (0.47) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL22648384 | 0.74 | ALDH1A1 (0.40) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |