Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ILK | Q13418 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355183 | 1.00 | KDM4E (0.54) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL5708098 | 0.92 | KDM4E (0.62) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL5708102 | 0.89 | KDM4E (0.49) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11676970 | 0.80 | KDM4E (0.58) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL2475992 | 0.80 | KDM4E (0.58) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL231307 | 0.78 | KDM4E (0.75) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL1069739 | 0.77 | CHAT (0.38) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL12776948 | 0.77 | KDM4E (0.43) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL12854008 | 0.76 | KDM4E (0.72) | KDM4ERAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL14373940 | 0.76 | RAB9A (0.67) | KDM4ERAB9ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250231165-A1 | DRUG PRODUCT SURROGATE SOLUTIONS | MODERNATX, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| EP-4419082-A1 | DRUG PRODUCT SURROGATE SOLUTIONS | ModernaTX, Inc. (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023069625-A1 | DRUG PRODUCT SURROGATE SOLUTIONS | MODERNATX, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-110187119-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-110187120-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110187121-B | Methods and compositions for the detection and treatment of preeclampsia | 耶鲁大学 | 2022-07-01 | — | — | CN | disclosed |
| US-11125758-B2 | Methods and kits for detecting misfolded proteins | YALE UNIVERSITY (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210255192-A1 | METHODS AND KITS FOR DETECTING MISFOLDED PROTEINS | YALE UNIVERSITY (US) | 2021-08-19 | — | — | US | disclosed |
| CN-104777307-B | The method and composition of pre-eclampsia detection and treatment | 耶鲁大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-110208540-A | The method and composition of preeclampsia detection and treatment | 耶鲁大学 | 2019-09-06 | — | — | CN | disclosed |
| CN-102483418-B | Methods and compositions for the detection and treatment of preeclampsia | UNIV YALE | 2015-01-07 | — | — | CN | disclosed |
| CN-102483418-A | Methods and compositions for the detection and treatment of preeclampsia | UNIV YALE | 2012-05-30 | — | — | CN | disclosed |
| WO-2010062377-A2 | METHODS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF PREECLAMPSIA | YALE UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |
| EP-1325067-B1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEM CO (US) | 2006-09-06 | — | — | EP | disclosed |
| CN-1469894-A | Multi-component optically brightened polyolefin blend | �Ϻ���ͨ��ѧ | 2004-01-21 | — | — | CN | disclosed |
| EP-1325067-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2003-07-09 | — | — | EP | disclosed |
| US-6492032-B1 | MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS | EASTMAN CHEMICAL COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-2002031035-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2002-04-18 | — | — | WO | disclosed |
| WO-2001010854-A1 | BENZOTHIAZOLE COMPOUNDS AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-02-15 | — | — | WO | disclosed |
| US-4169810-A | BENZOXAZOLYLSTILBENE, BENZOTHIAZOLYLSTILBENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-02 | — | — | US | disclosed |