Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ILK | Q13418 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355189 | 0.89 | KDM4E (0.54) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3355183 | 0.89 | KDM4E (0.54) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5708098 | 0.81 | KDM4E (0.62) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL17270111 | 0.74 | ILK (0.62) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27536788 | 0.74 | SMN1; SMN2 (0.46) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL231307 | 0.74 | KDM4E (0.75) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12776948 | 0.73 | KDM4E (0.43) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2475992 | 0.72 | KDM4E (0.58) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11676970 | 0.72 | KDM4E (0.58) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12854008 | 0.72 | KDM4E (0.72) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325067-B1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEM CO (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1325067-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2003-07-09 | — | — | EP | disclosed |
| US-6492032-B1 | MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS | EASTMAN CHEMICAL COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-2002031035-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2002-04-18 | — | — | WO | disclosed |
| US-4363744-A | Mixtures of optical brighteners and their use for the optical brightening | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | disclosed |
| US-4363744-A | Mixtures of optical brighteners and their use for the optical brightening | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-14 | — | — | US | disclosed |
| US-4169810-A | BENZOXAZOLYLSTILBENE, BENZOTHIAZOLYLSTILBENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-02 | — | — | US | disclosed |