Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.30 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246983 | 1.00 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL5390312 | 1.00 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL30213620 | 1.00 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL561726 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL81285 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL3181354 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL9420677 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL2387556 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL1951204 | 0.90 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Benzene SCHEMBL6890099 | 0.89 | TDP1 (1.00) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380853-A | Preparation method of 4-pyrazole boronic acid pinacol ester | 南京焕然生物科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-112851680-B | Indole drug molecule for medical nursing sterilization and disinfection, and preparation method and application thereof | 河南科技大学第一附属医院 | 2021-12-24 | — | — | CN | claimed |
| CN-113024592-A | Synthetic method of azetidine silicon precursor compound and method for synthesizing six-membered silicon nitrogen heterocyclic compound by using same | 四川大学 | 2021-06-25 | — | — | CN | claimed |
| CN-112851680-A | Indole drug molecule for medical nursing sterilization and disinfection, and preparation method and application thereof | 河南科技大学第一附属医院 | 2021-05-28 | — | — | CN | claimed |
| CN-110511189-A | 5- amino -1,2,4- furodiazole derivative and its synthetic method | UNIV GUANGXI SCI & TECHNOLOGY | 2019-11-29 | — | — | CN | claimed |
| CN-110467568-A | A kind of synthetic method of aryl quinoline derivatives | UNIV WENZHOU | 2019-11-19 | — | — | CN | claimed |
| CN-108408715-B | Situ Nitrogen Doping graphite acetylenic material and its synthetic method and application | 四川大学 | 2019-11-15 | — | — | CN | claimed |
| CN-107118781-B | A kind of synthetic method of liquid crystal media | 浙江工业大学 | 2019-11-12 | — | — | CN | claimed |
| CN-110408011-A | A kind of two isoquinolin of second y-bend, four ketone polymer and the preparation method and application thereof | INST CHEMISTRY CAS | 2019-11-05 | — | — | CN | claimed |
| CN-108129433-B | A kind of synthetic method of Cephanolide B | 陕西师范大学 | 2019-10-25 | — | — | CN | claimed |
| CN-101440076-A | Process for synthesizing optical activity 2-(1'(Z) alkenyl iodo-alkyl) tetrahydrofuran | UNIV ZHEJIANG (CN) | 2009-05-27 | — | — | CN | claimed |
| CN-101381424-A | Polyacetylene high molecule containing imidazole side group | UNIV WUHAN (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-101314634-A | Polygonal line type water-soluble aryleneethynylene, preparation and application thereof | UNIV NANJING POSTS & TELECOMM (CN) | 2008-12-03 | — | — | CN | claimed |
| CN-101230267-A | Fluorescent chemical sensor as well as preparation and detection method thereof | UNIV ZHEJIANG (CN) | 2008-07-30 | — | — | CN | claimed |
| CN-101222950-A | Processes for production of 4-(biphenylyl)azetidin-2-one phosphonic acids | MICROBIA INC (US) | 2008-07-16 | — | — | CN | claimed |
| CN-101151256-A | Process for production of dibenzoxepin derivative | KYOWA HAKKO KOGYO KK (JP) | 2008-03-26 | — | — | CN | claimed |
| CN-1662536-A | Alkynylpurine compounds and production methods thereof | SUMITOMO CHEMICAL CO (JP) | 2005-08-31 | — | — | CN | claimed |
| US-6498271-B2 | BIOTRANSFORMATION OF AN OLEFINIC MONOCARBOXYLIC ACID (OLEIC ACID) TO THE 1,18-OCTADEC-9-ENEDIOIC ACID IN PRESENCE OF CANDIDA TROPICALIS, A YEAST STRAIN, FOLLOWED BY CARBOXYLATON OF INTERMEDIATE BY REACTION WITH CARBON MONOXIDE AND WATER | GENERAL ELECTRIC COMPANY | 2002-12-24 | — | — | US | claimed |
| US-20020169339-A1 | Tricarboxylic acids, method, and branched polycarbonates prepared therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-11-14 | — | — | US | claimed |
| US-4956507-A | GRIGNARD REAGENTS FROM P-HALOFLUOROBENZENE AND MAGNESIUM COUPLING TO FORM P,P*-DIFLUOROBIPHENYL | PHILLIPS PETROLEUM COMPANY (US) | 1990-09-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169339-A1 | Tricarboxylic acids, method, and branched polycarbonates prepared therefrom | HADHB, HADHA, NOTUM | TDP1 1938/4885CYP3A4 420/4885ESR1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.