Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.65 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19941789 | 0.86 | RAB9A (0.61) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL10151628 | 0.84 | RAB9A (0.66) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL3268365 | 0.82 | SMN1; SMN2 (0.47) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL13986778 | 0.82 | TRPV1 (0.55) | LOXL2MAPTSMN1; SMN2TP53TRPV1 | |
| SCHEMBL15724733 | 0.82 | MAPT (0.47) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL12600035 | 0.82 | SMN1; SMN2 (0.47) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL203263 | 0.82 | MAPT (0.47) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL19067624 | 0.81 | MAPT (0.46) | LOXL2MAPTSMN1; SMN2TP53TRPV1 | |
| SCHEMBL3250178 | 0.80 | LOXL2 (0.67) | LOXL2UBE2TASIC3MAPTSMN1; SMN2 | |
| SCHEMBL24234046 | 0.79 | MAPT (0.45) | LOXL2MAPTSMN1; SMN2TP53TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |