Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355712 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7764064 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL3356400 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7767263 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9129772 | 0.78 | CYP4F2 (0.52) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL612174 | 0.74 | TSHR (0.63) | ALDH1A1HPGDMEN1KMT2ATSHR | |
| SCHEMBL17708695 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL17708693 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL22621901 | 0.71 | BRD4 (0.41) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7636320 | 0.70 | CYP4F2 (0.67) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |