Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 4/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514108 | 0.81 | SLC7A5 (0.44) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL1514088 | 0.81 | SLC7A5 (0.44) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL7730688 | 0.81 | SLC7A5 (0.35) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| Threonine SCHEMBL2076958 | 0.79 | NOS3 (0.37) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL11512679 | 0.78 | GSR (0.47) | — | |
| Alanine SCHEMBL5168125 | 0.78 | SLC7A5 (0.42) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL135879 | 0.78 | SLC7A5 (0.41) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL1537267 | 0.78 | SLC7A5 (0.41) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| Glycine SCHEMBL8005617 | 0.78 | SLC7A5 (0.41) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL352049 | 0.77 | SLC1A5 (0.43) | P2RY10GPR174SLC7A5SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099169-A1 | GENETIC SELECTION SYSTEM FOR IMPROVING RECOMBINANT PROTEIN EXPRESSION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-04-22 | — | — | US | disclosed |