Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308401 | 0.89 | ALDH1A1 (0.37) | ALDH1A1AIMP2 | |
| SCHEMBL3357781 | 0.88 | ALDH1A1 (0.40) | ALDH1A1SIRT1SIRT2CHRM1 | |
| SCHEMBL3355499 | 0.88 | ALDH1A1 (0.42) | ALDH1A1SIRT1SIRT2CHRM1AIMP2 | |
| SCHEMBL3354313 | 0.87 | ALDH1A1 (0.40) | ALDH1A1SIRT1SIRT2CHRM1AIMP2 | |
| SCHEMBL3355500 | 0.87 | ALDH1A1 (0.38) | ALDH1A1SIRT1SIRT2CHRM1AIMP2 | |
| SCHEMBL3355740 | 0.85 | ALDH1A1 (0.38) | ALDH1A1SIRT1SIRT2CHRM1 | |
| SCHEMBL3359218 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SIRT1SIRT2CHRM1AIMP2 | |
| SCHEMBL3351145 | 0.81 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL3355341 | 0.80 | ALDH1A1 (0.34) | ALDH1A1SIRT1SIRT2 | |
| SCHEMBL3359075 | 0.79 | ALDH1A1 (0.33) | ALDH1A1SIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | disclosed |
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | disclosed |
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | KHAMRAI UTTAM | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152160-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | CCR1, CCR4, CCR5 | ALDH1A1 903/4885SIRT1 1521/4885SIRT2 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.