Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809214 | 0.83 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL16042367 | 0.83 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10316251 | 0.79 | OPRM1 (0.69) | OPRM1OPRK1OPRL1CHRNB4CHRNA3 | |
| SCHEMBL2675331 | 0.79 | ATAD2 (0.52) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5121645 | 0.77 | OPRM1 (0.45) | OPRM1OPRK1OPRL1CHRNB4CHRNA3 | |
| SCHEMBL31714558 | 0.76 | OPRM1 (0.46) | OPRM1OPRK1OPRL1 | |
| SCHEMBL12991998 | 0.75 | ATAD2 (0.41) | — | |
| SCHEMBL5999430 | 0.75 | OPRM1 (0.49) | OPRM1OPRK1OPRL1CHRNB4CHRNA3 | |
| SCHEMBL13841066 | 0.74 | OPRM1 (0.56) | OPRM1OPRK1OPRL1CHRNB4CHRNA3 | |
| SCHEMBL11927508 | 0.74 | NOTUM (0.56) | OPRM1OPRK1OPRL1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |