Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799527 | 0.85 | NQO2 (0.52) | NQO2TRPM4CYP1A2CYP2A6BCHE | |
| SCHEMBL20362410 | 0.84 | RXRA (0.42) | NQO2TRPM4CYP1A2CYP2A6TRPA1 | |
| SCHEMBL2806194 | 0.82 | NQO2 (0.57) | NQO2TRPM4CYP1A2BCHEPTPN1 | |
| SCHEMBL29977590 | 0.82 | NQO2 (0.57) | NQO2TRPM4CYP1A2BCHEPTPN1 | |
| SCHEMBL15345404 | 0.80 | NQO2 (0.55) | NQO2TRPM4CYP1A2BCHEPTPN1 | |
| SCHEMBL10746784 | 0.80 | NQO2 (0.55) | NQO2TRPM4CYP1A2BCHEPTPN1 | |
| SCHEMBL14051803 | 0.79 | PTGS2 (0.51) | BCHELMNAHTTTP53ESR1 | |
| SCHEMBL3359160 | 0.78 | CYP1A2 (0.53) | CYP1A2CYP2A6TRPA1ESR1HSD17B1 | |
| SCHEMBL17919574 | 0.78 | CYP1A2 (0.48) | TRPM4CYP1A2CYP2A6HTR6GAA | |
| SCHEMBL16539783 | 0.78 | AKR1B1 (0.49) | NQO2TRPM4CYP1A2BCHEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |
| CN-101412775-B | Catalyst precursor for polymerization of propylene or combined polymerization, and preparation thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-12-22 | — | — | CN | disclosed |
| CN-101139407-B | Catalyst precursor for ethylene polymerization or copolymerization and preparation method thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-10-06 | — | — | CN | disclosed |
| US-20100209810-A1 | POLYMER ELECTROLYTE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| CN-101802932-A | Polymer electrolyte composition | SUMITOMO CHEMICAL CO | 2010-08-11 | — | — | CN | disclosed |
| EP-2192597-A1 | POLYMER ELECTROLYTE COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| CN-101412775-A | Catalyst activity component for polymerization of propylene or combined polymerization, catalyst precursor containing the same and preparation thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2009-04-22 | — | — | CN | disclosed |
| US-7514520-B2 | Process for producing phosphonitrilic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20080091050-A1 | Process For Producing Phosphonitrilic Acid Ester | ASAHI KASEI CHEMICAL CORPORATION (JP) | 2008-04-17 | — | — | US | disclosed |
| CN-101139407-A | Catalyst active component for ethylene polymerization or copolymerization and catalyst precursor comprising the active component and preparation method thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2008-03-12 | — | — | CN | disclosed |
| US-20070060739-A1 | Process for producing phosphonitrilic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2007-03-15 | — | — | US | disclosed |
| CN-1798753-A | Process for producing phosphonitrilic acid ester | ASAHI CHEMICAL CORP (JP) | 2006-07-05 | — | — | CN | disclosed |
| CN-1475473-A | Low-melt viscosity naphthol phenolic aldehyde prepolymer and synthesis method thereof | 北京玻璃钢研究设计院 | 2004-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080091050-A1 | Process For Producing Phosphonitrilic Acid Ester | PHOSPHO1, GNPAT, SELENOI | NQO2 2791/4885TRPM4 1721/4885CYP1A2 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.