Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873839 | 0.87 | KMT2A (0.54) | HTR7CDC7PLGPLAUKRAS | |
| SCHEMBL2870320 | 0.87 | KMT2A (0.54) | HTR7CDC7PLGPLAUKRAS | |
| SCHEMBL13139566 | 0.86 | HTR7 (0.53) | HTR7CDC7PLGPLAUKRAS | |
| SCHEMBL3356863 | 0.82 | HTR7 (0.50) | HTR7CDC7PLGPLAUKRAS | |
| SCHEMBL3354019 | 0.82 | HTR7 (0.50) | HTR7KRASARCYP1A2KMT2A | |
| SCHEMBL3356633 | 0.82 | HTR7 (0.50) | HTR7CDC7KRASARCYP1A2 | |
| SCHEMBL1122247 | 0.80 | ALDH1A1 (0.52) | HTR7KMT2ANPC1MAPTLMNA | |
| SCHEMBL1122380 | 0.79 | HTR7 (0.58) | HTR7CDC7PLGPLAUAR | |
| SCHEMBL23631701 | 0.79 | KRAS (0.46) | HTR7CDC7KRASARKMT2A | |
| SCHEMBL3062365 | 0.79 | HTR7 (0.47) | HTR7CDC7KRASARCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |