Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2748518 | 0.76 | KDM4C (0.38) | MEN1KMT2ATRPA1THRBCSF1R | |
| SCHEMBL2748271 | 0.73 | MEN1 (0.43) | MEN1KMT2ATRPA1THRBCSF1R | |
| SCHEMBL2748797 | 0.73 | KDM4C (0.45) | MEN1KMT2ATRPA1THRBMAP3K7 | |
| SCHEMBL2747947 | 0.73 | TRPA1 (0.40) | MEN1KMT2ATRPA1THRBMAP3K7 | |
| SCHEMBL2749079 | 0.73 | KMT2A (0.45) | MEN1KMT2ATRPA1MAP3K7TAB1 | |
| SCHEMBL2748398 | 0.72 | TRPA1 (0.37) | MEN1KMT2ATRPA1THRBMAP3K7 | |
| SCHEMBL2748394 | 0.72 | TRPA1 (0.37) | MEN1KMT2ATRPA1THRBMAP3K7 | |
| SCHEMBL2748675 | 0.71 | RHEB (0.43) | TRPA1MAP3K7TAB1CSF1RKDR | |
| SCHEMBL2748586 | 0.70 | TRPA1 (0.40) | MEN1KMT2ATRPA1THRBCSF1R | |
| SCHEMBL2747995 | 0.65 | TK1 (0.36) | MEN1KMT2AMAP3K7TAB1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036910-A1 | HEART PROTECTION BY ADMINISTERING AN AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | OHTA YOSHIKAZU (JP) | 2010-04-01 | — | — | WO | disclosed |