Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | RARG | P13631 | 3/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL9127352 | 0.96 | KDM4E (0.55) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| Ethylene Glycol SCHEMBL7527989 | 0.91 | KDM4E (0.59) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| Terephthalic Acid SCHEMBL7993200 | 0.89 | KDM4E (0.57) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL18758 | 0.86 | KDM4E (0.68) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL29594563 | 0.86 | KDM4E (0.68) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL29359975 | 0.86 | KDM4E (0.68) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6916181 | 0.86 | KDM4E (0.68) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| Alcohol SCHEMBL28996062 | 0.84 | KDM4E (0.62) | KDM4EGRIN2DGRIN2AGRIN2BGRIN2C | |
| Terephthalic Acid SCHEMBL1478940 | 0.84 | TSHR (0.67) | TSHRTP53ALDH1A1CA12CA1 | |
| Terephthalic Acid SCHEMBL2846917 | 0.84 | TSHR (0.67) | KDM4EPTPN1TSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273850-B2 | Blend of polypropylene-2,6-naphthalate (PPN) and a copolyester of PPN with a C4-C12 aliphatic diacid, along with phosphorus containing stabilizer; acceptably high glass transition temperatures for \"green\" content renewable polymer | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100151167-A1 | POLYESTER COMPOSITIONS FROM BIOLOGICALLY-DERIVED MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-17 | — | — | US | disclosed |
| US-20100151165-A1 | POLYESTER COMPOSITIONS FROM BIOLOGICALLY-DERIVED MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-17 | — | — | US | disclosed |