Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488830 | 0.70 | CYP2C19 (0.39) | SMN1; SMN2HRH1CYP3A4HTR2ACYP2C19 | |
| SCHEMBL3261585 | 0.66 | CYP2C19 (0.36) | LMNASLC6A3SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL1469953 | 0.65 | CYP3A4 (0.61) | SIGMAR1LMNAADRA1ASLC6A3KCNH2 | |
| SCHEMBL8366747 | 0.65 | CYP3A4 (0.61) | SIGMAR1LMNAADRA1ASLC6A3KCNH2 | |
| SCHEMBL9019451 | 0.65 | CYP3A4 (0.61) | SIGMAR1LMNAADRA1ASLC6A3KCNH2 | |
| SCHEMBL27850764 | 0.63 | SIGMAR1 (0.45) | SIGMAR1LMNAADRA1ASLC6A3KCNH2 | |
| SCHEMBL3258485 | 0.63 | KDM4E (0.40) | LMNACYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30104387 | 0.63 | CYP3A4 (0.33) | CYP3A4CYP2C19ALDH1A1MEN1ALOX15 | |
| SCHEMBL2587221 | 0.63 | MIF (0.42) | LMNASMN1; SMN2ADRA2CADRA2ACYP2C19 | |
| SCHEMBL15295377 | 0.63 | CYP3A4 (0.33) | CYP3A4CYP2C19ALDH1A1MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8505840-B2 | Method for modifying nomal clay and a method for producing composite elastomer from the clay | PHOMI MCM CO., LTD. (CN) | 2013-08-13 | — | — | US | disclosed |
| US-20100098495-A1 | Method for modifying Nomal Clay and a method for Producing Composite Elastomer from the Clay | PHOMI MCM CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |