Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335396 | 0.85 | F7 (0.44) | F7F3F9 | |
| SCHEMBL336443 | 0.82 | SMN1; SMN2 (0.43) | ACP1ABL1FABP6 | |
| SCHEMBL335501 | 0.81 | NPC1 (0.43) | F7F3MAPK1F9ACP1 | |
| SCHEMBL15282285 | 0.81 | ACP1 (0.46) | F7F3MAPK1ACP1ABL1 | |
| SCHEMBL15282212 | 0.81 | ACP1 (0.46) | F7F3MAPK1ACP1ABL1 | |
| SCHEMBL334912 | 0.80 | F7 (0.40) | F7F3F9ACP1ABL1 | |
| SCHEMBL336014 | 0.80 | ABL1 (0.41) | F7F3MAPK1F9ACP1 | |
| SCHEMBL336367 | 0.80 | MAPT (0.47) | F7MAPK1F9ACP1ABL1 | |
| SCHEMBL334843 | 0.79 | KDR (0.45) | F7F9F11ABL1FABP6 | |
| SCHEMBL335878 | 0.79 | ABL1 (0.43) | F7F3MAPK1F9ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |