Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29266573 | 0.83 | ESR1 (0.36) | ESR1ESR2MAOBALDH1A1PTPN1 | |
| SCHEMBL5855991 | 0.73 | CYP19A1 (0.47) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL5854730 | 0.72 | CYP19A1 (0.38) | CYP19A1ESR1ESR2MAOBCYP3A4 | |
| SCHEMBL29099783 | 0.71 | PTPN1 (0.53) | CYP19A1ESR1MAOBALDH1A1ALOX15 | |
| SCHEMBL1500280 | 0.70 | CYP19A1 (0.48) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL31525604 | 0.70 | CYP19A1 (0.48) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL28439793 | 0.69 | MAOB (0.44) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL4618569 | 0.69 | CYP19A1 (0.47) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL4618571 | 0.69 | CYP19A1 (0.47) | CYP19A1MAOBCYP3A4MAPTHPGD | |
| SCHEMBL7236035 | 0.68 | HTR1A (0.40) | CYP19A1MAOBCYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039679-A1 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2010-04-08 | — | — | WO | disclosed |