Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13518173 | 0.74 | — | — | |
| SCHEMBL4921731 | 0.74 | — | — | |
| SCHEMBL6485155 | 0.73 | — | — | |
| SCHEMBL7504371 | 0.72 | SRC (0.30) | — | |
| SCHEMBL4915979 | 0.69 | — | — | |
| SCHEMBL11703464 | 0.69 | — | — | |
| SCHEMBL819437 | 0.69 | MAPT (0.32) | — | |
| SCHEMBL2423602 | 0.69 | — | — | |
| SCHEMBL440187 | 0.67 | — | — | |
| SCHEMBL5695838 | 0.67 | LTA4H (0.43) | LTA4HTSHRCA4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803945-B2 | Tetrahydropyridothiophenes | 4SC AG (DE) | 2010-09-28 | — | — | US | claimed |
| US-7723523-B2 | Tetrahydropyridothiophenes | 4SC AG (DE) | 2010-05-25 | — | — | US | claimed |
| US-20090270378-A1 | NOVEL TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2009-10-29 | — | — | US | claimed |
| EP-1753512-B1 | TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | claimed |
| US-20070244112-A1 | Novel tetrahydropyridothiophenes | ALTANA PHARMA AG (DE) | 2007-10-18 | — | — | US | claimed |
| EP-1753512-A2 | TETRAHYDROPYRIDOTHIOPHENES | Altana Pharma AG (DE) | 2007-02-21 | — | — | EP | claimed |
| WO-2005118071-A2 | TETRAHYDROPYRIDOTHIOPHENES | ALTANA PHARMA AG (DE) | 2005-12-15 | — | — | WO | claimed |
| EP-0685474-B1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1998-09-16 | — | — | EP | claimed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | claimed |
| CN-1055357-A | N-alkynes-2-chlorine-acetyl-phenyl derivative and the weedicide that contains this compound | CENTRAL GLASS CO LTD (JP) | 1991-10-16 | — | — | CN | claimed |
| CN-116554207-A | Organic compound containing imidazo-aza-phenyl group, and preparation method and application thereof | 烟台先进材料与绿色制造山东省实验室 | 2023-08-08 | — | — | CN | disclosed |
| US-11706981-B2 | Organic light emitting device and compounds for use in same | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-18 | — | — | US | disclosed |
| CN-109311904-B | Certain substituted benzofuro-and benzothienoquinolines for use in organic light emitting diodes | 出光兴产株式会社 | 2022-03-29 | — | — | CN | disclosed |
| US-20200227652-A1 | ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2020-07-16 | — | — | US | disclosed |
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| EP-0685474-A1 | Oxalylamino-benzofuran- and benzothienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| CN-1055357-A | N-alkynes-2-chlorine-acetyl-phenyl derivative and the weedicide that contains this compound | CENTRAL GLASS CO LTD (JP) | 1991-10-16 | — | — | CN | disclosed |
| CN-1055357-A | N-alkynes-2-chlorine-acetyl-phenyl derivative and the weedicide that contains this compound | CENTRAL GLASS CO LTD (JP) | 1991-10-16 | — | — | CN | disclosed |
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270378-A1 | NOVEL TETRAHYDROPYRIDOTHIOPHENES | BAX, BCL2, CCAR2 | LTA4H 2483/4885TSHR 1110/4885CA4 3763/4885 |
| US-11706981-B2 | Organic light emitting device and compounds for use in same | SLCO4C1, XPO6, ERCC1 | LTA4H 997/4885TSHR 3746/4885CA4 3492/4885 |
| US-20070244112-A1 | Novel tetrahydropyridothiophenes | BAX, BCL2, BAD | LTA4H 2501/4885TSHR 1335/4885CA4 3777/4885 |
| US-20200227652-A1 | ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME | SLCO4C1, XPO6, ERCC1 | LTA4H 997/4885TSHR 3746/4885CA4 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.