Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283117 | 0.74 | HDAC4 (0.34) | HDAC4OPRM1OPRK1OPRL1 | |
| SCHEMBL27449113 | 0.72 | HDAC4 (0.33) | HDAC4OPRM1OPRK1OPRL1 | |
| SCHEMBL8039521 | 0.72 | PNMT (0.39) | OPRM1 | |
| SCHEMBL4089733 | 0.71 | HDAC4 (0.36) | HDAC4HDAC9OPRM1OPRK1OPRL1 | |
| SCHEMBL276639 | 0.71 | HDAC4 (0.32) | HDAC4OPRM1OPRK1OPRL1 | |
| SCHEMBL5665863 | 0.71 | HDAC4 (0.32) | HDAC4OPRM1OPRK1OPRL1 | |
| SCHEMBL5715764 | 0.71 | MAOB (0.38) | HDAC4HDAC9OPRM1OPRK1OPRL1 | |
| SCHEMBL16163009 | 0.71 | HDAC4 (0.32) | HDAC4OPRM1OPRK1OPRL1 | |
| SCHEMBL9629458 | 0.71 | HDAC4 (0.36) | HDAC4HDAC9OPRM1OPRK1OPRL1 | |
| SCHEMBL8106039 | 0.71 | HDAC4 (0.32) | HDAC4OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |