SCHEMBL3357728

SCHEMBL3357728

CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
SOAT1 P35610 1/20 0.48
CNR1 P21554 5/20 0.46
CNR2 P34972 2/20 0.46
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 2/20 0.45
THRB P10828 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
MEN1 O00255 1/20 0.45
ALOX12 P18054 1/20 0.45
BLM P54132 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5807418 0.97 CNR1 (0.49) CNR1CNR2ALDH1A1MAPTHPGD
SCHEMBL25303134 0.97 EPHX2 (0.47) SOAT1CNR2MEN1KMT2AEPHX2
SCHEMBL1736038 0.97 EPHX2 (0.47) SOAT1CNR2MEN1KMT2AEPHX2
SCHEMBL3285881 0.90 DPP7 (0.44) MAPT
SCHEMBL3283700 0.90 DPP7 (0.44) MAPT
SCHEMBL11052070 0.90 DPP7 (0.44) MAPT
SCHEMBL539143 0.90 DPP7 (0.44) MAPT
SCHEMBL5183216 0.90 DPP7 (0.44) MAPT
SCHEMBL25303264 0.90 DPP7 (0.44) MAPT
SCHEMBL1690132 0.90 DPP7 (0.44) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890361-B Compositions containing linoleic acid 太阳星光齿磨公司 2023-02-24 CN disclosed
EP-2668939-B1 COMPOSITION CONTAINING POLYUNSATURATED FATTY ACID SUNSTAR INC (JP) 2020-06-17 EP disclosed
US-10472379-B2 Ruthenium-sphingomyelin complexes and methods for their use in the treatment of tumors GARNETT MCKEEN LAB, INC. 2019-11-12 US disclosed
EP-3533437-A1 COMPOSITION CONTAINING LINOLEIC ACID Sunstar Inc. (JP) 2019-09-04 EP disclosed
US-20190247290-A1 COMPOSITION CONTAINING LINOLEIC ACID SUNSTAR INC. (JP) 2019-08-15 US disclosed
US-20180051045-A1 RUTHENIUM-SPHINGOMYELIN COMPLEXES AND METHODS FOR THEIR USE IN THE TREATMENT OF TUMORS GARNETT MCKEEN LAB, INC. 2018-02-22 US disclosed
WO-2017200792-A1 RUTHENIUM-SPHINGOMYELIN COMPLEXES AND METHODS FOR THEIR USE IN THE TREATMENT OF TUMORS GARNETT MCKEEN LAB, INC. (US) 2017-11-23 WO disclosed
US-9605012-B2 Palladium-ruthenium-zinc-organo complexes and methods for their use in the treatment of inflammatory diseases GARNETT MCKEEN LABORATORY, INC. (US) 2017-03-28 US disclosed
CN-103338746-B Compositions containing polyunsaturated fatty acid SUNSTAR INC. (JP) 2015-12-23 CN disclosed
US-8940312-B2 Composition containing polyunsaturated fatty acid SUNSTAR INC. (JP) 2015-01-27 US disclosed
WO-2014164902-A1 PALLADIUM-RUTHENIUM-ZINC-ORGANO COMPLEXES AND METHODS FOR THEIR USE IN THE TREATMENT OF INFLAMMATORY DISEASES GARNETT MCKEEN LABORATORY, INC. (US) 2014-10-09 WO disclosed
EP-2668939-A1 COMPOSITION CONTAINING POLYUNSATURATED FATTY ACID SUNSTAR INC. (JP) 2013-12-04 EP disclosed
US-20130287827-A1 COMPOSITION CONTAINING POLYUNSATURATED FATTY ACID SUNSTAR INC. (JP) 2013-10-31 US disclosed
CN-103338746-A Composition containing polyunsaturated fatty acid SUNSTAR INC 2013-10-02 CN disclosed
WO-2010046542-A1 METHOD FOR PREPARING MODIFIED FIBER PRODUCTS OY KESKUSLABORATORIO - CENTRALLABORATORIUM AB (FI) 2010-04-29 WO disclosed
US-6669932-B2 Mixture of unsaturated fatty acid, phosphatides, antioxidizer, protein and mucopolysaccharides SUNSTAR INC. (JP) 2003-12-30 US disclosed
CN-1125634-C Skin-lightening cosmetic SUNSTAR INC (JP) 2003-10-29 CN disclosed
US-20030103916-A1 SKIN-WHITENING COSMETIC SUNSTAR INC. (JP) 2003-06-05 US disclosed
EP-0992236-B1 SKIN-LIGHTENING COSMETIC SUNSTAR INC (JP) 2003-04-02 EP disclosed
EP-0992236-A1 SKIN-LIGHTENING COSMETIC Sunstar Inc. (JP) 2000-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472379-B2 Ruthenium-sphingomyelin complexes and methods for their use in the treatment of tumors SGMS2, SGMS1, SMPD4 KDM4E 3334/4885SOAT1 53/4885CNR1 2952/4885
US-20180051045-A1 RUTHENIUM-SPHINGOMYELIN COMPLEXES AND METHODS FOR THEIR USE IN THE TREATMENT OF TUMORS SGMS2, SGMS1, SMPD4 KDM4E 3334/4885SOAT1 53/4885CNR1 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.